The segment would usually open with Yakko, Wakko, and Dot dashing through a park and then coming to a halt, with Yakko saying "It's that time again!" After Dot and Wakko would try to guess what it was time for, Yakko would say it was time to learn the lesson of the day and then bring out the titular wheel. He would then spin the wheel, while saying the rhyme: "Wheel of Morality, turn turn turn / Tell us the lesson that we should learn." After the wheel stopped on a certain number, it would print out the corresponding moral, which was always a goofy and nonsensical one, and Yakko would read it aloud. The Warners would often give some comments on the "moral". The segments always ended with Ralph the Guard blowing his whistle from offscreen and chasing the Warners away from the Wheel. One episode ended with the Yakko about to make his annoucement, only to have Dot and Wakko protest they are sick of this segment as the "lessons" are nonsense. When asked whose foolish idea it was in the first place, Yakko responds with "the executives at the Fox Kids Network", causing Wakko and Dot to suddenly stop complaining and feigning their support for the Wheel of Morality, implying the show will be cancelled should this segment be discontinued.
|Episode 2||Moral #2 - If at first you don't succeed, blame it on your parents.|
|Episode 4||Moral #4 - Never ask what hot dogs are made of.|
|Episode 9||Win $5,000!|
|Episode 18||Moral #1 - Brush your teeth after every meal. This moral brought to you by the American Dental Association.|
|Episode 23||Moral #4 - The answer, my friend, is blowing in the wind, except in New Jersey where what's blowing in the wind smells funny.|
|Episode 24||Moral #5 - If you can't say something nice, you're probably at the Ice Capades.|
|Episode 34||Moral #3 - Elvis lives on in our hearts, in his music, and in a trailer park outside Milwaukee.|
|Episode 35||Moral #3 - You can teach an old dog new tricks, but you can't teach Madonna to act.|
|Episode 39||Moral #5 - Early to rise and early to bed makes a man healthy, but socially dead.|
|Episode 40||Moral #1 - Vote early and vote often.|
|Episode 45||Moral #6 - Possums have pouches like kangaroos. (Even Yakko is confused by this one)|
|Episode 46||Moral #2 - Don't eat with your mouth full.|
|Episode 47||Win a Free Trip to Tahiti!|
|Episode 58||Moral #1 - Do not back up. Severe tire damage.|
|Episode 64||Moral #6 - Lather, rinse, repeat.|
|Episode 66||Moral #2 - Don't be a fool, stay in school.|
|Episode 67||Moral #3 - People who live in glass houses should get dressed with the lights out.|
|Episode 68||Moral #2 - Don't spit in public.|
|Episode 76||Moral #2 - 2B or not 2B, that is the pencil.|
|Wakko's Wish||Moral #5 - Just cheer up and never ever give up hope!|
- On the occasions where the wheel landed on the "$5,000" spot and the "Trip to Tahiti" spot, the Warners would cheer, "WE WON, WE WON, WE WON, WE WON!!!"
- The wheel never seemed to land on "7", "8", "Bankrupt", or "Lose a Turn" throughout any of its segments.
- Title Pun: Wheel Of Fortune
- In fact, in one episode, Wakko asks to buy a vowel, only for Yakko to remind him that this wasn't the same wheel.